My research focuses on the genetic basis of behavior, specifically tameness and aggression in the grasscutter (Thryonomys swinderianus), a rodent species native to West and Central Africa that serves as an important source of protein. Our study combines genetic data, including genotypes and polymorphisms, with behavioral assessments of tameness to identify genetic variants associated with calmer temperament. These insights will help guide the selection and breeding of tamer individuals to improve grasscutter performance under domestication.
In many regions in Ghana, grasscutters are still primarily hunted from the wild, a practice that contributes to forest fires, ecosystem disturbances, and zoonotic disease risks due to the species’ popularity as a delicacy. Although domestication efforts have increased over the past decade, the species’ aggressive behavior in captivity remains a major challenge, often resulting in injuries, deaths, and reduced production efficiency.
Our research aims to address these issues by identifying and selecting individuals that exhibit genetic markers linked to tameness. The ultimate goal is to develop a breeding and selection framework that enhances productivity and profitability for farmers while promoting environmental sustainability. Importantly, this approach relies entirely on natural genetic variation rather than genetic modification.
October 2024 - present: Postgraduate Student, Graduate School of Biological Sciences, Wildlife Research Center, Kyoto University, Japan.
August 2023 - April 2024: Youth Leaders Fellowship (YoLe Fellow), United Nations Population Fund - UNFPA Ghana, Accra, Ghana
November 2022 - August 2023: Research/Teaching Assistant, College of Basic and Applied Science, Department of Animal Science, University of Ghana.
August 2018 - Oct 2022: Bachelor of Science in Agriculture (Animal Science), College of Basic and Applied Science, Department of Animal Science, University of Ghana.
We are currently investigating three candidate genes in the grasscutter that have been linked to behavioral variation in other species: the androgen receptor gene, the oxytocin receptor gene, and the vasopressin receptor gene. These genes possess different types of polymorphisms in them that have been associated with traits such as aggression, social bonding, and other behavioral phenotypes across mammals.
In grasscutters, our study relates genetic data from these loci to behavioral measurements collected from captive-bred populations to evaluate how the specific variants influence temperament (Tameness). By quantifying both genotype and behavior, we hope to estimate not only whether these polymorphisms affect tameness but also the magnitude of their effects on this key domestication trait.
Ghana Grasscutter project (Enhancing Livelihoods in Ghana through Improvement in Native Livestock Production)
https://grasscutter.sakuraweb.com/
Graduate School of Science
Wildlife Research Center, Kyoto University
2-24 Tanaka-Sekiden-cho, Sakyo, Kyoto, 606-8203, Japan, Kyoto University
azimeyxorlali [at] gmail [dot] com / azimey [dot] xorlali [dot] 68y [at] st [dot] kyoto-u [dot] ac [dot] jp


